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Pianist and composer Koki Nakano shares his second single Treg from his forthcoming album Oceanic Feeling - out 13th May 2022.
The human immune system has an ability to attack and destroy "non-self" cells, such as cells infected with viruses or bacteria. But when proper control mechanisms are not working, it also destroys the healthy cells of oneself, and thus causes autoimmune diseases. Tregs (regulatory T cells) are immune cells that work to prevent such a false destruction of healthy cells.
Tregs also play an important role in establishing a pregnancy. An embryo that has both a father-derived trait (transplant antigen) and a mother-derived transplant antigen becomes a semi-foreign substance "non-self" to the mother, and should be rejected originally, but the function of Tregs establishes fetomaternal immune tolerance and enables the maintenance and continuation of pregnancy.
This sort of function that our body originally has, seems to imply that we exist in a very delicate balance between self-retention and tolerance to accept others.
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Le pianiste et compositeur Koki Nakano dévoile "Treg", le deuxième single de son prochain album Oceanic Feeling, disponible le 13 mai 2022.
Le système immunitaire humain a la capacité d'attaquer et de détruire les cellules "étrangères", comme les cellules infectées par des virus ou des bactéries. Mais lorsque les mécanismes de contrôle ne fonctionnent pas, il détruit également les cellules saines non-étrangères, et provoque ainsi des maladies auto-immunes. Les Tregs (cellules T régulatrices) sont des cellules immunitaires qui s'efforcent d'empêcher une destruction erronée de cellules saines.
Les Tregs jouent également un rôle important dans l'établissement d'une grossesse. Un embryon qui possède à la fois un trait dérivé du père (antigène de transplantation) et un antigène de transplantation dérivé de la mère devient une substance semi-étrangère, soit "étrangère" pour la mère, et devrait être rejeté à l'origine, mais les Tregs établissent une tolérance immunitaire fœto-maternelle et permettent le maintien et la poursuite de la grossesse.
Ce type de fonction que notre corps possède à l'origine semble impliquer que nous existons dans un équilibre très délicat entre la rétention de soi et la tolérance pour accepter les autres.
credits
released February 11, 2022
Composed by Koki Nakano
Recorded, mixed by François Baurin at Hinterland Lab studio
Mastering by Alexis Bardinet at Globe Audio Mastering
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